Phosphodiesterases and Their Inhibitors,
Spiros Liras, Andrew S. Bell, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug.
Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE targets and their inhibitors. Drug development options for all major human PDE families are discussed and cover diverse therapeutic fields, such as neurological/psychiatric, cardiovascular/metabolic, pain, and allergy/respiratory diseases. Finally, emerging chemotherapeutic applications of PDE inhibitors against malaria and other tropical diseases are discussed.
Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE targets and their inhibitors. Drug development options for all major human PDE families are discussed and cover diverse therapeutic fields, such as neurological/psychiatric, cardiovascular/metabolic, pain, and allergy/respiratory diseases. Finally, emerging chemotherapeutic applications of PDE inhibitors against malaria and other tropical diseases are discussed.
种类:
年:
2014
出版:
1
出版社:
Wiley-VCH
语言:
english
页:
240
ISBN 10:
3527332197
ISBN 13:
9783527332199
系列:
Methods and Principles in Medicinal Chemistry Volume 61
文件:
PDF, 11.71 MB
IPFS:
,
english, 2014
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